Chi-Chen Lin

Chi-Chen Lin
Professor
Doctor of Basic Medicine, National Cheng Kung University
Room 1208, 12th Floor, Bioscience Building / Immunology Laboratory
(04)22840896＃132
lincc@dragon.nchu.edu.tw

Research areas

腫瘤免疫學, 自體免疫學, 天然物及有機化學合成藥物生物活性之探討
主要研究方向，包括:
1. 免疫樹狀細胞 (dendritic cells)於癌症及自體免疫疾病之細胞分子生物機轉及其於免疫治療之應用
2. 免疫疾病及癌症動物模式之建立
3. DNA疫苗之開發

Courses offering

上學期-核糖核酸疫苗特論(2學分)
上學期-高等免疫學(3學分)
上學期-細胞及分子免疫學(2學分)
下學期-基因治療特論(2學分)
下學期-動物細胞培養(3學分)
下學期-疫苗學(2學分)

Academic Works

A. 期刊論文

  1. Chuang CH, Cheng YC, Li S, Lin SC, Lehman CW, Chen DY, Tsai SW, Lin CC*. Atractylodin suppresses dendritic cell maturation and ameliorates collagen-induced arthritis in a mouse model.J Agric Food Chem. 2019 Jun 2.(SCI)
  2. Tan KT, Hsieh TY, Chao YH, Li JP, Lan JF, Lin CC*, Chen DY.Apoptosis in patients with primary antiphospholipid antibody syndrome.International Journal of Rheumatic Diseases. 2018, Dec, accept (SCI)
  3. Wu PC, Chou WH, Lin SC, Lehman CW, Lien CZ, Wu CS, Lin CC*. Sclareol attenuates the development of atopic dermatitis induced by 2,4-dinitrochlorobenzene in mice.  Immunopharmacology and Immunotoxicology. 2018, Dec, accept (SCI)
  4. Lin YC, Su JH, Lin SC, Chang CC, Hsia TC, Tung YT, Lin CC*. A Soft Coral-Derived Compound, 11-Dehydrosinulariolide, Induces G2/M Cell-Cycle Arrest and Apoptosis in Small Cell Lung Cancer. Marine Drugs. 2018, Nov, accept (SCI)
  5. Li WS, Chu CL, Cgen MH, Lue YS, Lai RS, You BJ, Lin CC*. Lepista sordida Water Extract Enhances Maturation of Dendritic Cells in Vitro and In Vivo.  Iranian Journal of Immunology. 2018, Nov, accept (SCI)
  6. Hsieh MC, Tsai WH, Jheng YP, Su SL, Wang SY, Lin CC, Chen YH, Chang WW. The beneficial effects of Lactobacillus reuteri ADR-1 or ADR-3 consumption on type 2 diabetes mellitus: a randomized, double-blinded, placebo-controlled trial. Sci Rep. 2018 Nov 14;8(1):16791 (SCI)
  7. Chao CH, Cheng JC, Gonçalves TP, Huang KW, Lin CC, Huang HC, Hwang SY, Wu YC.  Glaulactams A-C, daphniphyllum alkaloids from Daphniphyllum glaucescens. Sci Rep. 2018 Oct 18;8(1):15417. (SCI)
  8. Li JM, Tseng CW, Lin CC, Law CH, Chien YA, Kuo WH, Chou HC, Wang WC, Chan HL. Upregulation of LGALS1 is associated with oral cancer metastasis. Ther Adv Med Oncol. 2018 Aug 24;10:1758835918794622. doi: 10.1177/1758835918794622. eCollection 2018. (SCI)
  9. Yang G, Li S, Yang Y, Yuan L, Wang P, Zhao H, Ho CT, Lin CC*. Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by Regulating the Expression of Ki-67 and Proliferating Cell Nuclear Antigen and the Differentiation of CD4+ T Cells through Mitogen-Activated Protein Kinase Signaling Pathways. J Agric Food Chem. 2018 Aug 8;66(31):8299-8306. doi: 10.1021/acs.jafc.8b02524. Epub 2018 Jul 30. (SCI)
  10. Ahmed AF, Chen YW, Huang CY, Tseng YJ, Lin CC, Dai CF, Wu YC, Sheu JH. Isolation and Structure Elucidation of Cembranoids from a Dongsha  Atoll Soft Coral Sarcophyton stellatum. Marine Drugs. 2018, Jun 14;16(6). pii: E210. doi: 10.3390/md16060210. (SCI)
  11. Chao YH, Chen DY, Lan JL, Tan KT, Lin CC*. Tolerogenic β2-glycoprotein I DNA Vaccine and FK506 as an Adjuvant Attenuates Experimental Obstetric Antiphospholipid Syndrome. PLoS One. 2018, Jun 12; 13(6):e0198821.  doi: 10.1371/journal.pone.0198821. eCollection 2018. (SCI)
  12. Lee SW, Lien HC, Lin CC, Wen MC, Chang CS. Low Expression of Transforming Growth Factor β in the Epithelium of Barrett's Esophagus. Gastroenterology Res. 2018 Jun;11(3):189-194. doi: 10.14740/gr1009w. Epub 2018 May 31. (SCI)
  13. Lin CC*, Wu JJ, Pan YG, Chao YH, Lin FC, Lee YR, Chu CL. Gold Lotion from Citrus Peel Extract Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis in murine. J Sci Food Agric. 2018 Apr 24. doi: 10.1002/jsfa.9097. (SCI)
  14. Tsai SW, Hsieh MC, Li S, Lin SC, Wang SP, Lehman CW, Lien CZ, Lin CC*. Therapeutic Potential of Sclareol in Experimental Models of Rheumatoid Arthritis. Int J Mol Sci. 2018 May 3;19(5). (SCI)
  15. Lin MX, Lin SH, Li YR, Chao YH, Lin CH, Su JH, Lin CC*. Lobocrassin B Induces Apoptosis of Human Lung Cancer and Inhibits Tumor Xenograft Growth. Mar Drugs. 2017 Dec 4;15(12). pii: E378. doi: 10.3390/md15120378. (SCI)
  16. LI YR, Li S, Lin CC*. Effect of Resveratrol and Pterostilbene on Aging and Longevity. Biofactor. 2018 Jan;44(1):69-82. doi: 10.1002/biof.1400. Epub 2017 Dec 6. (SCI)
  17. Lai KH, You WJ, Lin CC,  El-Shazly M, Liao ZJ, Su JH.Anti-Inflammatory Cembranoids from the Soft CoralLobophytum crassum. 2017. Nov.Mar. Drugs , 15(10), 327 (SCI)
  18. Pan YG, Yu YL, Lin CC, Lanier L, Chu CL. FceRI gamma-chain Negatively Modulates Dectin-1 Responses in Dendritic Cells. Frontiers in Immunology. 2017 Oct 27;8:1424. doi: 10.3389/fimmu.2017.01424. eCollection 2017. (SCI)
  19. Chen DY*, Lin CC*, Chen YM,Chao YH, Yang DH. Dextromethorphan Exhibits Anti-inflammatory and Immunomodulatory Effects in a Murine Model of Collagen-Induced Arthritis and in Human Rheumatoid Arthritis. Sci Rep. 2017 Sep 12;7(1):11353 (SCI)
  20. Chung TW, Li YR, Huang WY, Su JH, Chan HL, Lin SH, Liu CS, Lin SC, Lin CC*, Lin CH*. Sinulariolide suppresses LPS‑induced phenotypic and functional maturation of dendritic cells.Mol Med Rep. 2017 Sep 13 (SCI)
  21. Liu YL, Lin LC, Tung YT, Ho ST, Chen YL, Lin CC*, Wu JH*.Rhododendron oldhamii leaf extract improves fatty liver syndrome by increasing lipid oxidation and decreasing the lipogenesis pathway in mice. Int. J. Med. Sci. 2017.14(9):862–870 (SCI)
  22. Lin CC*, Chen DY*, Tang KT, Chao YH, Shen CH, Lui PW.Inhibitory effects of propofol on Th17 cell differentiation.Immunopharmacol Immunotoxicol. 2017 Aug;39(4):211-218(SCI)
  23. Chung TW, Lin SC, Su JH, Chen YK, Lin CC*, Chan HL*. Sinularin induces DNA damage, G2/M phase arrest, and apoptosis in human hepatocellular carcinoma cells.BMC Complement Altern Med. 2017 Jan 19;17(1):62 (SCI)
  24. Tang KT, Hsieh TY, Chao YH, Lin MX, Chen YH, Chen DY, Lin CC*. Plasma levels of high-mobility group box 1 and soluble receptor for advanced glycation end products in primary antiphospholipid antibody syndrome patients.PLoS One. 2017 May 30;12(5):e0178404 (SCI)
  25. Li YR, Lin CC, Huang CY, Wong YH, Hsieh CH, Wu HW, Chen JJW, Wu YS.Study of the inhibitory effects on TNF-α-induced NF-κB activation of IMD0354 analogs. Chem Biol Drug Des. 2017 May 30. (SCI)
  26. Hsieh CW, Chen YM, Lin CC, Tang KT, Chen HH, Hung WT, Lai KL, Chen DY..Elevated Expression of the NLRP3 Inflammasome and Its Correlation with Disease Activity in Adult-onset Still Disease.J Rheumatol. 2017 May 15 (SCI)
  27. Chen HH, Chen DY, Lin CC, Chen YM, Lai KL, Lin CH.Association between use of disease-modifying antirheumatic drugs and diabetes in patients with ankylosing spondylitis, rheumatoid arthritis, or psoriasis/psoriatic arthritis: a nationwide, population-based cohort study of 84,989 patients.Ther Clin Risk Manag. 2017 May 2;13:583-592.(SCI)
  28. Lin SC, Chen MC, Li S, Lin CC*, Wang TT*.Antiviral activity of nobiletin against chikungunya virus in vitro.Antivir Ther. 2017 Apr 13. (SCI)
  29. Hsieh YP, Chang CC, Kor CT, Yang Y, Wen YK, Chiu PF, Lin CC. Relationship between uric acid and technique failure in patients on continuous ambulatory peritoneal dialysis: a long-term observational cohort study.BMJ Open. 2017 Apr 7;7(4):e010816 (SCI)
  30. Hsieh YP, Tsai SM, Chang CC, Kor CT, Lin CC.Association between red cell distribution width and mortality in patients undergoing continuous ambulatory peritoneal dialysis.Sci Rep. 2017 Apr 3;7:45632. (SCI)
  31. Lin SC, Kappes MA, Chen MC, Lin CC*, Wang TT*.Distinct susceptibility and applicability of MDCK derivatives for influenza virus research.PLoS One. 2017 Feb 16;12(2):e0172299. (SCI)
  32. Lin SC, Ho CT, Chuo WH, Li S, Wang TT*, Lin CC*. Effective inhibition of MERS-CoV infection by resveratrol.BMC Infect Dis. 2017 Feb 13;17(1):144. (SCI)
  33. Lin PY, Tsai CT, Chuang WL, Chao YH, Pan IH, Chen YK, Lin CC*, Wang BY*.Chlorella sorokiniana induces mitochondrial-mediated apoptosis in human non-small cell lung cancer cells and inhibits xenograft tumor growth in vivo.BMC Complement Altern Med. 2017 Feb 1;17(1):88 (SCI)
  34. Wang SP, Lin SC, Li S, Chao YH, Hwang GY, Lin CC*. Potent Antiarthritic Properties of Phloretin in Murine Collagen-Induced Arthritis. Evid Based Complement Alternat Med. 2016;2016:9831263.(SCI)
  35. Chen DY, Chen YM, Chien HJ, Lin CC, Hsieh CW, Chen HH, Hung WT, Lai CC. Metabolic Disturbances in Adult-Onset Still's Disease Evaluated Using Liquid Chromatography/Mass Spectrometry-Based Metabolomic Analysis.PLoS One. 2016 Dec 22;11(12):e0168147.(SCI)
  36. Chen HC, Chang WT, Hseu YC, Chen HY, Chuang CH, Lin CC, Lee MS, Lin MK. Immunosuppressive Effect of Litsea cubeba L. Essential Oil on Dendritic Cell and Contact Hypersensitivity Responses.Int J Mol Sci. 2016 Aug 12;17(8).(SCI)
  37. Tang KT, Chao YH, Chen DY, Lim YP, Chen YM, Li YR, Yang DH, Lin CC*."Betahistine attenuates murine collagen-induced arthritis by suppressing both inflammatory and Th17 cell responses."Int Immunopharmacol. ,08,2016 (SCI)
  38. Tseng TS, Chuang SM, Hsiao NW, Chen YW, Lee YC, Lin CC, Huang C, Tsai KC. Discovery of a potent cyclooxygenase-2 inhibitor, S4, through docking-based pharmacophore screening, in vivo and in vitro estimations.Mol Biosyst. 2016 Jul 19;12(8):2541-51(SCI)
  39. Chen HH, Chao YH, Chen DY, Yang DH, Chung TW, Li YR, Lin CC*, “Oral administration of acarbose ameliorates imiquimod-induced psoriasis-like dermatitis in a mouse model,” Int Immunopharmacol, 04 2016. (SCI)
  40. Tsai SW, Tung YT, Chen HL, Yang SH, Liu CY, Lu M, Pai HJ, Lin CC, Chen CM. Myostatin propeptide gene delivery by gene gun ameliorates muscle atrophy in a rat model of botulinum toxin-induced nerve denervation.Life Sci. 2016 Feb 1;146:15-23 (SCI)
  41. Hsu SY, Liou JW, Cheng TL, Peng SY, Lin CC, Chu YY, Luo WC, Huang ZK, Jiang SJ. , “beta-Naphthoflavone protects from peritonitis by reducing TNF-alpha-induced endothelial cell activation. ,” Pharmacological Research , 12 2015. (SCI)
  42. Li YR, Chen DY, Chu CL, Li S, Chen YK, Wu CL, Lin CC*. , “Naringenin inhibits dendritic cell maturation and has therapeutic effects in a murine model of collagen-induced arthritis ,” The Journal of Nutritional Biochemistry, 12 2015. (SCI)
  43. Chen HH, Chen DY, Chao YH, Chen YM, Wu CL, Lai KL, Lin CH, Lin CC*. , “Acarbose Decreases the Rheumatoid Arthritis Risk of Diabetic Patients and Attenuates the Incidence and Severity of Collagen-induced Arthritis in Mice. ,” Scientific Reports , 12 2015. (SCI)
  44. Lin MK, Lee MS, Chang WT, Chen HY, Chen JF, Li YR, Lin CC*, Wu TS*. , “Immunosuppressive effect of zhankuic acid C from Taiwanofungus camphoratus on dendritic cell activation and the contact hypersensitivity response,” Bioorganic & Medicinal Chemistry Letters , 10 2015. (SCI)
  45. Chen Y, Chen YM, Lin CC, Hsieh CW, Wu YC, Hung WT, Chen HH, Lan JL, “The potential role of advanced glycation end products (AGEs) and soluble receptors for AGEs (sRAGE) in the pathogenesis of adult-onset still's disease.,” BMC Musculoskelet Disord. , vol.16, no.1, pp.11, 05 2015. (SCI)
  46. Chuang WL, Su CC, Lin PY, Lin CC, Chen YL., “Sann-Joong-Kuey-Jian-Tang induces autophagy in HepG2 cells via regulation of the phosphoinositide-3 kinase/Akt/mammalian target of rapamycin and p38 mitogen-activated protein kinase pathways.,” Mol Med Rep, 2015 Aug;12(2):1677-84. doi: 10.3892/mmr.2015.3573. Epub 2015 Mar 31. (SCI)
  47. Chen DY, Chen YM, Hsieh TY, Hsieh CW, Lin CC, Lan JL, “Significant effects of biologic therapy on lipid profiles and insulin resistance in patients with rheumatoid arthritis.,” Arthritis Res Ther., vol.17(1):559, 03 2015. (SCI)
  48. Lin CC*, Pan IH, Li YR, Pan YG, Lin MK, Lu YH, Wu HC, Chu CL, “The Adjuvant Effects of High-Molecule-Weight Polysaccharides Purified from Antrodia cinnamomea on Dendritic Cell Function and DNA Vaccines,” PLoS One, vol.10(2), pp.e0116191, 02 2015. (SCI)
  49. Ho ST, Tung YT, Kuo YH, Lin CC*, Wu JH*, “Ferruginol inhibits non-small cell lung cancer growth by inducing caspase-associated apoptosis.,” Integr Cancer Ther, vol.14(1), pp.86-97, 01 2015. (SCI)
  50. Chen SY, Shiau AL, Li YT, Lin CC, Jou IM, Liu MF, Wu CL, Wang CR, “Transcription factor snail regulates tumor necrosis factor α-mediated synovial fibroblast activation in the rheumatoid joint,” Arthritis Rheumatol. , vol.67(1):, pp.39-50, 01 2015. (SCI)
  51. Lin CC*, Chen JT*, Lin MW*, Chan CH*, Wen YF, Wu SB, Chung TW, Lyu KW, Chou HC, Chan HL.Identification of protein expression alterations in gefitinib-resistant human lung adenocarcinoma: PCNT and mPR play key roles in the development of gefitinib-associated resistance.Toxicol Appl Pharmacol. 2015 Nov 1;288(3):359-73 (SCI)
  52. .Li S, Lin YC, HoCT, Lin PY, Pan IH, Michiko S, Wang HC, Chu CL, Chen DY, Lin CC*, “Formulated Extract from Multiple Citrus Peels Impairs Dendritic Cell Functions and Attenuates Allergic Contact Hypersensitivity,” International Immunopharmacology, 2014 May;20(1):12-23. doi: 10.1016/j.intimp.2014.02.005. Epub 2014 Feb 22. (SCI)
  53. Chen DY, Yao L, Chen YM, Lin CC, Huang KC, Chen ST, Lan JJ, Hsieh SL, “A Potential Role of Myeloid DAP12-Associating Lectin (MDL)-1 in the Regulation of Inflammation in Rheumatoid Arthritis Patients,” PLOSone, 2014 Jan 21;9(1):e86105. doi: 10.1371/journal.pone.0086105. eCollection 2014. (SCI)
  54. Huang HJ*, Lin CC*, Chou HC, Chen YW, Lin ST, Lin YC, Lin DY, Lyu KW, Chan HL.Proteomic analysis of rhein-induced cyt: ER stress mediates cell death in breast cancer cells.Mol Biosyst. 2014 Dec;10(12):3086-100 (SCI)
  55. Weng TY, Huang SS, Yen MC, Lin CC, Chen YL, Lin CM, Chen WC, Wang CY, Chang JY, Lai MD, “A Novel Cancer Therapeutic Using Thrombospondin 1 in Dendritic Cells.,” Molecular Therapy, 2014 Feb;22(2):292-302. doi: 10.1038/mt.2013.236. Epub 2013 Oct 15. (SCI)
  56. Chen DY, Song PS, Hong JS, Chu CL, Pan IH, Chen YM, Lin CH, Lin SH, Lin CC* , “ Dextromethorphan Inhibits Activations and Functions in Dendritic Cells,” Clinical and Developmental Immunology, 2013;2013:125643. doi: 10.1155/2013/125643. Epub 2013 May 28. (SCI)
  57. Chen DY*, Lin CC*, Chen YM, Lan JL, Hung, WT, Chen HH, Lai KL, Hsieh CW, “Involvement of TLR7 MyD88-dependent signaling pathway in the pathogenesis of adult-onset Still's disease,” Arthritis Research & Therapy, 2013 Mar 4;15(2):R39. doi: 10.1186/ar4193. (SCI)
  58. Li YT, Chen SY, Wang CR, Liu MF, Lin CC, Jou IM, Shiau AL, Wu CL, “Amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223.,” Arthritis Rheum., 2012 Oct;64(10):3240-5. doi: 10.1002/art.34550. (SCI)
  59. Huang HC, Chen YR, Lin CC*., “Antrodia cinnamomea (a. camphorata, neu chang chih): an exceptional polypore mushroom with potential antitumor and immuno-modulatory effects.,” Current Topics In Nutraceutical Research. 2012,10(1). (SCI)
  60. Huang ZT*,Yen MC*, Lin CC, Weng TY, Chen YL, Lin CM, Lai MD., “Skin delivery of short hairpin RNA of indoleamine 2,3 dioxygenase induces anti-tumor immunity against orthotopic and metastatic liver cancer,” Cancer Science, 09 2011. (SCI)
  61. Chen DY, Chen YM, Chen HH, Hsieh CW, Lin CC, Lan JL., “Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-alpha therapy,” Arthritis Research & Therapy, vol.13 (4), pp.R 126, 07 2011. (SCI)
  62. Lin CC*, Yu YL, Shih CC, Liu KJ, Hong LZ, Chen Jody D.C. Chu CL, “A Novel Adjuvant Ling Zhi-8 Enhances the Efficacy of DNA Cancer Vaccine by Activating Dendritic Cells,” Cancer Immunology Immunotherapy, vol.60 (7), pp.1019-1027, 07 2011. (SCI)
  63. Wang ST, Chang CC, Yen MC, Tu CF, Chu CL, Peng YT, Chen DY, Lan JL, Lin CC*, “RNA interference-mediated silencing of Foxo3 in antigen-presenting cells as a strategy for the enhancement of DNA vaccine potency.,” Gene Therapy, vol.18 (4), pp.372-383, 04 2011. (SCI)
  64. Chen DY, Shen GH, Chen YM, Chen HH, Lin CC, Hsieh CW, Lan JL, “Interferon-inducible protein-10 as a marker to detect latent and active tuberculosis in rheumatoid arthritis,” The International Journal of Tuberculosis and Lung Disease, vol.15 (2), pp.192-199, 02 2011. (SCI)
  65. Chen SY, Wu CL, Lai MD, Lin CC, Yo YT, Jou IM, Lee CH, Weng CT, Shiau AL, Wang CR, “Amelioration of Rat Collagen-induced Arthritis through CD4+ T Cells Apoptosis and Synovial Interleukin-17 Reduction by Indoleamine 2,3-dioxygenase,” Human Gene Therapy, vol.22 (2), pp.145-154, 02 2011. (SCI)
  66. Chu CL, Chen DC, Lin CC*., “A Novel Adjuvant Ling Zhi-8 for Cancer DNA Vaccines. (Invited Commentary),” Human Vaccine, vol.7 (11), 2011. (SCI)
  67. Huang CS, Chang CC, Lin CM, Wang ST, Wu MT, Li IC, Chang HS, Lin CC*. , “Promoting effect of antrodia camphorata as an immunomodulating adjuvant on the antitumor efficacy of Her-2/neu dna vaccine. Cancer Immunology Immunotherapy,” Cancer Immunology Immunotherapy, vol.59 (8), pp.1259-1272, 08 2010. (SCI)
  68. Yen MC, Lin CC, Chen YL, Huang SS, Yang HJ, Chang CP, Lei HY, Lai MD., “A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA,” Clinical Cancer Research, vol.15 (2), pp.641-649, 01 2009. (SCI)
  69. Lin CC*, Yen MC, Lin CM, Huang SS, Yang HJ, Chow NH, Lai MD., “Delivery of noncarrier naked DNA vaccine into the skin by supersonic flow induces a polarized T helper type 1 immune response to cancer,” The Journal of Gene Medicine , vol.10 (6), pp.679-689, 06 2008. (SCI)
  70. Lin CC*, Yang HJ, Tu CF, Lai MD., “The opposing effects of lipopolysaccharide on the antitumor therapeutic efficacy of DNA vaccine,” DNA and Cell Biology, vol.27 (3), pp.151-157, 03 2008. (SCI)
  71. Lin CC*, Tu CF, Yen MC, Chen MC, Hsieh WJ, Chang WC, Chang WT, Lai MD., “Inhibitor of heat-shock protein 90 enhances the antitumor effect of DNA vaccine targeting clients of heat-shock protein,” Molecular Therapy, vol.15 (2), pp.404-410, 02 2007. (SCI)
  72. Tu CF#, Lin CC#, Chen MC, Ko TM, Lin CM, Wang YC, Lai MD. , “Autologous neu DNA vaccine can be as effective as xenogenic neu DNA vaccine by altering administration route,” Vaccine, vol.25 (4), pp.719-728, 01 2007. (SCI)
  73. Lin CC*, Chou CW, Shiau AL, Tu CF, Ko TM, Chen YL, Yang BC, Tao MH, Lai MD. , “Therapeutic HER2/Neu DNA vaccine inhibits mouse tumor naturally overexpressing endogenous neu,” Molecular Therapy, vol.10 (2), pp.290-301, 08 2004. (SCI)

 

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