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林季千

林季千
教授
國立成功大學博士
生科大樓12樓1208室
(04)22840896#132
lincc@dragon.nchu.edu.tw

研究領域

腫瘤免疫學, 自體免疫學, 天然物及有機化學合成藥物生物活性之探討
主要研究方向,包括:
1. 免疫樹狀細胞 (dendritic cells)於癌症及自體免疫疾病之細胞分子生物機轉及其於免疫治療之應用
2. 免疫疾病及癌症動物模式之建立
3. DNA疫苗之開發

教授科目

上學期-核糖核酸疫苗特論(2學分)
上學期-高等免疫學(3學分)
上學期-細胞及分子免疫學(2學分)
下學期-基因治療特論(2學分)
下學期-動物細胞培養(3學分)
下學期-疫苗學(2學分)

學術著作

A. 期刊論文

  1. Chuang CH, Cheng YC, Li S, Lin SC, Lehman CW, Chen DY, Tsai SW, Lin CC*. Atractylodin suppresses dendritic cell maturation and ameliorates collagen-induced arthritis in a mouse model.J Agric Food Chem. 2019 Jun 2.(SCI)
  2. Tan KT, Hsieh TY, Chao YH, Li JP, Lan JF, Lin CC*, Chen DY.Apoptosis in patients with primary antiphospholipid antibody syndrome.International Journal of Rheumatic Diseases. 2018, Dec, accept (SCI)
  3. Wu PC, Chou WH, Lin SC, Lehman CW, Lien CZ, Wu CS, Lin CC*. Sclareol attenuates the development of atopic dermatitis induced by 2,4-dinitrochlorobenzene in mice.  Immunopharmacology and Immunotoxicology. 2018, Dec, accept (SCI)
  4. Lin YC, Su JH, Lin SC, Chang CC, Hsia TC, Tung YT, Lin CC*. A Soft Coral-Derived Compound, 11-Dehydrosinulariolide, Induces G2/M Cell-Cycle Arrest and Apoptosis in Small Cell Lung Cancer. Marine Drugs. 2018, Nov, accept (SCI)
  5. Li WS, Chu CL, Cgen MH, Lue YS, Lai RS, You BJ, Lin CC*. Lepista sordida Water Extract Enhances Maturation of Dendritic Cells in Vitro and In Vivo.  Iranian Journal of Immunology. 2018, Nov, accept (SCI)
  6. Hsieh MC, Tsai WH, Jheng YP, Su SL, Wang SY, Lin CC, Chen YH, Chang WW. The beneficial effects of Lactobacillus reuteri ADR-1 or ADR-3 consumption on type 2 diabetes mellitus: a randomized, double-blinded, placebo-controlled trial. Sci Rep. 2018 Nov 14;8(1):16791 (SCI)
  7. Chao CH, Cheng JC, Gonçalves TP, Huang KW, Lin CC, Huang HC, Hwang SY, Wu YC.  Glaulactams A-C, daphniphyllum alkaloids from Daphniphyllum glaucescens. Sci Rep. 2018 Oct 18;8(1):15417. (SCI)
  8. Li JM, Tseng CW, Lin CC, Law CH, Chien YA, Kuo WH, Chou HC, Wang WC, Chan HL. Upregulation of LGALS1 is associated with oral cancer metastasis. Ther Adv Med Oncol. 2018 Aug 24;10:1758835918794622. doi: 10.1177/1758835918794622. eCollection 2018. (SCI)
  9. Yang G, Li S, Yang Y, Yuan L, Wang P, Zhao H, Ho CT, Lin CC*. Nobiletin and 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone Ameliorate 12- O-Tetradecanoylphorbol-13-acetate-Induced Psoriasis-Like Mouse Skin Lesions by Regulating the Expression of Ki-67 and Proliferating Cell Nuclear Antigen and the Differentiation of CD4+ T Cells through Mitogen-Activated Protein Kinase Signaling Pathways. J Agric Food Chem. 2018 Aug 8;66(31):8299-8306. doi: 10.1021/acs.jafc.8b02524. Epub 2018 Jul 30. (SCI)
  10. Ahmed AF, Chen YW, Huang CY, Tseng YJ, Lin CC, Dai CF, Wu YC, Sheu JH. Isolation and Structure Elucidation of Cembranoids from a Dongsha  Atoll Soft Coral Sarcophyton stellatum. Marine Drugs. 2018, Jun 14;16(6). pii: E210. doi: 10.3390/md16060210. (SCI)
  11. Chao YH, Chen DY, Lan JL, Tan KT, Lin CC*. Tolerogenic β2-glycoprotein I DNA Vaccine and FK506 as an Adjuvant Attenuates Experimental Obstetric Antiphospholipid Syndrome. PLoS One. 2018, Jun 12; 13(6):e0198821.  doi: 10.1371/journal.pone.0198821. eCollection 2018. (SCI)
  12. Lee SW, Lien HC, Lin CC, Wen MC, Chang CS. Low Expression of Transforming Growth Factor β in the Epithelium of Barrett's Esophagus. Gastroenterology Res. 2018 Jun;11(3):189-194. doi: 10.14740/gr1009w. Epub 2018 May 31. (SCI)
  13. Lin CC*, Wu JJ, Pan YG, Chao YH, Lin FC, Lee YR, Chu CL. Gold Lotion from Citrus Peel Extract Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis in murine. J Sci Food Agric. 2018 Apr 24. doi: 10.1002/jsfa.9097. (SCI)
  14. Tsai SW, Hsieh MC, Li S, Lin SC, Wang SP, Lehman CW, Lien CZ, Lin CC*. Therapeutic Potential of Sclareol in Experimental Models of Rheumatoid Arthritis. Int J Mol Sci. 2018 May 3;19(5). (SCI)
  15. Lin MX, Lin SH, Li YR, Chao YH, Lin CH, Su JH, Lin CC*. Lobocrassin B Induces Apoptosis of Human Lung Cancer and Inhibits Tumor Xenograft Growth. Mar Drugs. 2017 Dec 4;15(12). pii: E378. doi: 10.3390/md15120378. (SCI)
  16. LI YR, Li S, Lin CC*. Effect of Resveratrol and Pterostilbene on Aging and Longevity. Biofactor. 2018 Jan;44(1):69-82. doi: 10.1002/biof.1400. Epub 2017 Dec 6. (SCI)
  17. Lai KH, You WJ, Lin CC,  El-Shazly M, Liao ZJ, Su JH.Anti-Inflammatory Cembranoids from the Soft CoralLobophytum crassum. 2017. Nov.Mar. Drugs , 15(10), 327 (SCI)
  18. Pan YG, Yu YL, Lin CC, Lanier L, Chu CL. FceRI gamma-chain Negatively Modulates Dectin-1 Responses in Dendritic Cells. Frontiers in Immunology. 2017 Oct 27;8:1424. doi: 10.3389/fimmu.2017.01424. eCollection 2017. (SCI)
  19. Chen DY*, Lin CC*, Chen YM,Chao YH, Yang DH. Dextromethorphan Exhibits Anti-inflammatory and Immunomodulatory Effects in a Murine Model of Collagen-Induced Arthritis and in Human Rheumatoid Arthritis. Sci Rep. 2017 Sep 12;7(1):11353 (SCI)

 

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