移至主內容

張嘉哲

張嘉哲
教授
美國約翰霍普金斯大學博士
生科大樓11樓1106室/ 癌化機制與抑癌藥物研究室
(04)22840896#115
chiachechang@gmail.com

研究領域

腫瘤生物學 藥物毒理學 細胞生長與凋亡 基因剔除技術

教授科目

上學期-抗癌藥物機制導論

上學期-基因功能分析導論

上學期-腫瘤訊息傳導

上學期-細胞生理特論

下學期-抑癌基因特論

下學期-生醫英文論文撰寫

下學期-腫瘤遺傳學暨基因體學導論

簡要經歷

教授   國立中興大學生物醫學研究所 2013 ~ 迄今

導師   國立中興大學生命科學院碩士在職專班 2016 ~ 迄今

所長   國立中興大學生物醫學研究所 2013 ~ 2016

組長   國立中興大學研究發展處計畫業務組 2010 ~ 2016

副教授  國立中興大學生物醫學研究所 2008 ~ 2013

助理教授  國立中興大學生物醫學研究所 2002 ~ 2008

博士後研究  加拿大安大略省癌症中心免疫學系 2000 ~ 2002 

哲學博士 美國約翰霍普金斯大學醫學院生物化學系 1994 ~ 2000 

獲獎項目

2001年加拿大國家癌症研究所博士後研究fellowship
2001年加拿大國家衛生研究院博士後研究fellowship
1999年美國約翰霍普金斯大學醫學院年輕學者著作獎
1993年中華民國教育部公費留學考試通過

 

指導研究生獲獎 
2004年指導研究生周怡云榮獲國立中興大學生命科學院研究生獎學金

學術著作

A.指標期刊論文 (IF is based on 2015 JCR)

  1. Or CR, Chang Y, Lin WC, Lee WC, Su HL, Cheung MW, Huang CP, Ho C, Chang CC (2017) Obatoclax, a pan-BCL-2 inhibitor, targets cyclin d1 for degradation to induce antiproliferation in human colorectal carcinoma cells. International Journal of Molecular Sciences 18(1): 44; doi:10.3390/ijms18010044. (January 2017) (SCI)

  2. Or CR, Su HL, Lee WC, Yang SY, Ho C, Chang CC (2016) Diphenhydramine induces melanoma cell apoptosis by suppressing STAT3/MCL-1 survival signaling and retards B16-F10 melanoma growth in vivo. Oncology Reports 36: 3465-3471. (December 2016) (SCI)

  3. Ho TF, Chang CC (2015) A promising “TRAIL” of tanshinones for cancer therapy. BioMedicine (Taipei) 5:29-35. (December, 2015)

  4. Chang CC, Kuan CP, Lin JY, Lai JS, Ho TF (2015) Tanshinone IIA facilitates TRAIL sensitization by up-regulating DR5 through the ROS-JNK-CHOP signaling axis in human ovarian carcinoma cell lines. Chemical Research in Toxicology 28:1574–1583. (August, 2015) [IF: 3.529; 10/59=16.94% (Chemistry, Medicinal)]

  5. Chung YK, Or RCH, Lu CH, Ouyang WT, Yang SY, Chang CC* (2015) Sulforaphane down-regulates SKP2 to stabilize p27KIP1 for inducing antiproliferation in human colon adenocarcinoma cells. Journal of Bioscience and Bioengineering 199:35-42. (January 2015) (SCI) (*: corresponding author) [IF: 1.884; 39/123=31.70% (Food Science & Technology)]

  6. Lin KW, Huang AM, Lin CC, Chang CC, Hsu WC, Hour TC, Pu YS, Lin CN (2014) Anti-cancer effects of ursane triterpenoid as a single agent and in combination with cisplatin in bladder cancer. European Journal of Pharmacology 740:742-751. (October 2014) (SCI) [IF: 2.532; 113/254=44.48% (Pharmacology & Pharmacy)]

  7. Chang CY, Shen CY, Kang CK, Sher YP, Sheu WHH, Chang CC*, Lee TH (2014) Taurine protects HK-2 cells from oxidized LDL-induced cytotoxicity via the ROS-mediated mitochondrial and p53-related apoptotic pathways. Toxicology and Applied Pharmacology 279:351-63. (September 15, 2014) (SCI) (*: corresponding author) [IF: 3.705; 13/87=14.94% (Toxicology)]

  8. Chang CC, Lai JS, Tsai CS, Ma SW, Lin JY, Huang LR, Lu CH, Liao EC, Ho TF (2013) Proapoptotic and TRAIL-sensitizing constituents isolated from Salvia militiorrhiza (Danshen). Journal of Bioscience and Bioengineering 116:516-523. (October 2013) (SCI) [IF: 1.884; 39/123=31.70% (Food Science & Technology)]

  9. Chen WC, Yu WJ, Chang CC, Chang JS, Huang SH, Chang CH, Chen SY, Chien CC, Yao CL, Chen WM, Wei YH (2013) Enhancing production of prodigiosin from Serratia marcescens C3 by statistical experimental design and porous carrier addition strategy. Biochemical Engineering Journal 78:93-100. (September 2013) (SCI) [IF: 2.467; 32/134=23.88% (Engineering, Chemical)]

  10. Chen HP, Shieh JJ, Chang CC, Chen TT, Lin JT, Wu MS, Lin JH, Wu CY (2013) Metformin decreases hepatocellular carcinoma risk in a dose-dependent manner: population-based and in vitro studies. Gut 62:606-615. (April 2013) (SCI) [IF: 14.660; 2/76=2.63% (Gastroenterology & Hepatology)]

  11. Yang SY, Wang HM, Wu TW, Chen YJ, Shieh JJ, Lin JH, Ho TF, Luo RJ, Chen CY, Chang CC* (2013) Subamolide B isolated from medicinal plant Cinnamomum subavenium induces cytotoxicity in human cutaneous squamous cell carcinoma cells through mitochondrial and CHOP-dependent cell death pathways. Evidence-Based Complementary and Alternative Medicine 2013:630415. doi:10.1155/2013/630415. (March 2013) (SCI) (*: corresponding author) [IF: 1.880; 7/24=29.16% (Integrative & Complementary Medicine)]

  12. Huang SW, Wu CY, Wang YT, Kao JK, Lin CC, Chang CC, Mu SW, Chen YY, Chiu HW, Chang CH, Liang SM, Chen YJ, Huang JL, Shieh JJ (2013) p53 modulates the AMPK inhibitor compound C induced apoptosis in human skin cancer cells. Toxicology and Applied Pharmacology 267:113-124. (Feb. 15th, 2013) (SCI) [IF: 3.705; 13/87=14.94% (Toxicology)]

  13. Pan MY, Shen YC, Lu CH, Yang SY, Ho TF, Peng YT, Chang CC* (2012) Prodigiosin activates endoplasmic reticulum stress cell death pathway in human breast carcinoma cell lines. Toxicology and Applied Pharmacology 265:325-334. (December 15th, 2012) (SCI)        (*: corresponding author) [IF: 3.705; 13/87=14.94% (Toxicology)]

  14. Lai JK, Wu HC, Shen YC, Hsieh HY, Yang SY, Chang CC* (2012) Krüppel-like factor 4 is involved in cell scattering induced by hepatocyte growth factor. Journal of Cell Science 125:4853-4864. (Oct. 15th, 2012) (SCI) (*: corresponding author) [IF: 5.432; 41/184=22.28% (Cell Biology)]

  15. Hsieh HY, Shieh JJ, Chen CJ, Pan MY, Yang SY, Lin SC, Chang JS, Lee AYL, Chang CC* (2012) Prodigiosin down-regulates SKP2 to induce p27KIP1 stabilization and antiproliferation in human lung adenocarcinoma cells. British Journal of Pharmacology 166: 2095-2108. (August,  2012) (SCI) (*: corresponding author) [IF: 4.842; 24/254=9.44% (Pharmacology & Pharmacy)]

  16. Lu CH, Lin SC, Yang SY, Pan MY, Lin YW, Hsu CY, Wei YH, Chang JS, Chang CC* (2012) Prodigiosin-induced cytotoxicity involves RAD51 down-regulation through the JNK and p38 MAPK pathways in human breast carcinoma cell lines. Toxicology Letters 212:83-89. (July 7th, 2012) (SCI) (*: corresponding author) [IF: 3.262; 21/87=24.13% (Toxicology)]

  17. Huang SW, Chang CC, Lin CC, Tsai JJ, Chen YJ, Wu CY, Liu KT, Shieh JJ (2012) Mcl-1 determines the imiquimod-induced apoptosis but not imiquimod-induced autophagy in skin cancer cells. Journal of Dermatological Science 65:170-178. (March, 2012) (SCI) [IF: 3.419; 9/62=14.51% (Dermatology)]

  18. Kuan CP*, Huang HC, Chang CC**, Lu YL (2012) TaqMan real-time PCR for detection and quantitation of squash leaf curl virus in cucurbits. Journal Virological Methods 179:367-372. (February, 2012) (SCI) (**: Co-corresponding author) [IF: 1.781; 93/162=57.40% (Biotechnology & Applied Microbiology)]

  19. Chang CC, Wang YH, Chern CM, Liou KT, Hou YC, Peng YT, Shen YC. (2011) Prodigiosin inhibits gp91phox and iNOS expression to protect mice against the oxidative/nitrosative brain injury induced by hypoxia-ischemia. Toxicology and Applied Pharmacology 257:137-147. (November, 2011) (SCI) [IF: 3.705; 13/87=14.94% (Toxicology)]

  20. Chang CC§, Chen WC§, Ho TF, Wu HS, Wei YH (2011) Development of natural anti-tumor drugs by microorganisms. Journal of Bioscience and Bioengineering 111:501-511. (May, 2011) (SCI) (§:equal contribution) [IF: 1.884; 39/123=31.70% (Food Science & Technology)]

  21. Wang ST§, Chang CC§, Yen MC, Tu CF, Chu CL, Peng YT, Chen DY, Lan JL, Lin CC (2011) RNA interference-mediated silencing of Foxo3 in antigen-presenting cells as a strategy for the enhancement of DNA vaccine potency. Gene Therapy 18:373-383. (April, 2011) (SCI)  (§:equal contribution) [IF:3.104; 47/162=29.01% (Biotechnology & Applied Microbiology)]

  22. Fu TY, Chang CC, Lin CT, Lai CH, Peng SY, Ko YJ, Tang PC (2011) Let-7b-mediated suppression of basigin expression and metastasis in mouse melanoma cells. Experimental Cell Research 317:445-451. (February 15th, 2011) (SCI) [IF: 3.246; 86/211=40.75% (Oncology)]

  23. Lu CH, Chang CC, Chang MC, Chen SJ, Jan YJ, Fu TF, Ho ES (2011) Clinical parameters associated with unsatisfactory specimens of conventional cervical smears. Diagnostic Cytopathology 39:87-91. (February 2011) (SCI) [IF: 1.121; 22/30=73.33% (Medical Laboratory Technology)]

  24. Lu CH, Chang CC, Ho ES, Chen SJ, Lin SJ, Fu TF, Chang MC (2010) Should adequacy criteria in cervicovaginal cytology be modified after radiotherapy, chemotherapy, or hysterectomy? Cancer Cytopathology 118(6):474-481. (December 25th, 2010) (SCI) [IF: 3.354; 16/75=21.33% (Pathology)]

  25. Huang SW, Liu KT, Chang CC, Chen YJ, Wu CY, Tsai JJ, Lu WC, Wang YT, Liu CM, Shieh JJ (2010) Imiquimod simultaneously induces autophagy and apoptosis in human basal cell carcinoma cells. British Journal of Dermatology 163:310-320. (August, 2010) (SCI) [IF: 4.275; 6/62=9.67% (Dermatology)]

  26. Huang CH, Chang CC, Lin CM, Wang ST, Wu MT, Li EIC, Chang HC, Lin CC (2010) Promoting effect of Antrodia camphorate as an immunomodulating adjuvant on the antitumor efficacy of HER-2/neu DNA vaccine. Cancer Immunology Immunotherapy 59:1259–1272. (August, 2010) (SCI) [IF: 3.941; 41/148=27.70% (Immunology)]

  27. Kao WC, Wu JY, Chang CC, Chang JS (2009) Cadmium biosorption by polyvinyl alcohol immobilized recombinant Escherichia coli. Journal of Hazardous Materials 169:651-658. (September, 2009) (SCI) [IF: 4.529; 2/124=1.61% (Engineering, Civil)]

  28. Ko JC, Ciou SC, Jhan JY, Cheng CM, Su YJ, Chuang SM, Lin ST, Chang CC, Lin YW (2009) Roles of MKK1/2-ERK1/2 and phosphoinositide 3-kinase-AKT signaling pathways in erlotinib-induced Rad51 suppression and cytotoxicity in human non-small cell lung cancer cells. Molecular Cancer Research 7:1378-1389. (August, 2009) (SCI) [IF: 4.380; 44/211=20.85% (Oncology)]

  29. Ho TF, Peng YT, Chuang SM, Lin SC, Feng BL, Lu CH, Yu WJ, Chang JS*, Chang CC* (2009) Prodigiosin down-regulates survivin to facilitate paclitaxel sensitization in human breast carcinoma cell lines. Toxicology and Applied Pharmacology 235:253-260. (March, 2009) (SCI) (*: corresponding author) [IF: 3.705; 13/87=14.94% (Toxicology)]

  30. Chang HW, Gu DL, Su SH, Chang CC, Cheng CA, Huang HW, Yao CT, Chou TC, Chuang LY, Cheng CC (2008) High-throughput gender identification of Accipitridae eagles with real-time PCR using TaqMan probes. Theriogenology 70:83–90. (July, 2008)(SCI)

  31. Chang HW, Chou TC, Gu DL, Cheng CA, Chang CC, Yao CT, Chuang LY. Wen CH, Chou YC, Tan KY, Cheng CC (2008) An improved PCR method for gender identification of eagles. Molecular & Cellular Probes 22:184-188. (June, 2008) (SCI)

  32. Chen YJ, Wu CY, Chang CC, Ma CJ, Li MC, Chen CM (2008) Nuclear Krüppel-like factor 4 expression is associated with human skin squamous cell carcinoma progression and metastasis. Cancer Biology & Therapy 7:779-784. (May, 2008) (SCI)

  33. Chang HW, Cheng CA, Gu DL, Chang CC, Su SH, Wen CH, Chou YC, Chou TC, Yao TY, Tsai CL, Cheng CC (2008) High-throughput avian molecular sexing by SYBR green-based real-time PCR combined with melting curve analysis. BMC Biotechnology 8:12. (Feb., 2008) (SCI)

  34. Lin GT, Tseng HF, Chang CK, Chuang LY, Liu CS, Yang CH, Tu CJ, Wang EC, Tan HT, Chang CC, Wen CH, Chen HC, Chang HW (2008) SNP combinations in chromosome-wide genes are associated with bone mineral density in Taiwanese women. Chinese Journal of Physiology 51:32-41. (Feb., 2008) (SCI)

  35. Ho TF, Ma CJ, Lu CH, Tsai YT, Wei YH, Chang JS, Lai JK, Cheuh PJ, Yeh CT, Tang PC, Chang JT, Ko JL, Liu FS, Yen HE, Chang CC* (2007) Undecylprodigiosin selectively induces apoptosis in human breast carcinoma cells independent of p53. Toxicology and Applied Pharmacology 225:318-328. (Dec., 2007) (*: corresponding author) (SCI) [IF: 3.705; 13/87=14.94% (Toxicology)]

  36. Kao WC, Chiu YP, Chang CC*, Chang JS* (2006) Localization effect on the metal biosorption capability of recombinant mammalian and fish metallothioneins in Escherichia coli. Biotechnology Progress 22:1256-1264. (Oct., 2006) (SCI) (*: corresponding author)

  37. Lin YF, Wu MS, Chang CC, Lin SW, Lin JT, Sun YJ, Chen DS, Chow LP (2006) Comparative immunoproteomics of identification and characterization of virulence factors from Helicobacter pylori related to gastric cancer. Molecular & Cellular Proteomics 5:1484 –1496. (Aug., 2006) (SCI)

  38. Lu CH, Liu FH, Kuo CJ, Chang CC, Ho, E. S.-C. (2006) Prediction of persistence or recurrence after conization for cervical intraepithelial neoplasia III. Obstetrics & Gynecology 107:830-835. (April, 2006) (SCI)

  39. Wang YH¶, Wang WY¶, Chang CC¶, Liou KT¶, Sung YJ, Liao JF, Chen CF, Chang, S, Hou YC, Chou YC, Shen YC (2006) Taxifolin ameliorates cerebral ischemia-reperfusion injury in rats through its anti-oxidative effect and modulation of NF-kappa B activation. (¶:equal contribution) Journal of Biomedical Sciences 13:127-141. (Jan., 2006) (SCI)

  40. Chang CC, Ou YC, Raung SL, Chen CJ (2005) Antiviral effect of dehydroepiandrosterone on Japanese encephalitis virus infection. Journal of General Virology 86:2513-2523. (Sept., 2005) (SCI)

  41. Hao Z, Duncan GS, Chang CC, Elia A, Fang M, Wakeham A, Okada H, Calzascia T, Jang Y, You-Ten A, Yeh WC, Ohashi P, Wang X, Mak TW (2005) Specific ablation of the apoptotic functions of cytochrome c reveals a differential requirement for cytochrome c and Apaf-1 in apoptosis. Cell 121: 579-591. (May, 2005) (SCI)

  42. Su CC, Chiu HH, Chang CC, Chen JC, Hsu SM (2004) CD30 is involved in inhibition of T-cell proliferation by Hodgkin’s Reed-Sternberg cells. Cancer Research 64:2148-2152. (March, 2004) (SCI)

  43. Chang CC, Warren D, Sacksteder K, Gould SJ (1999) PEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein import. The Journal of Cell Biology 147:761-773. (Nov., 1999) (SCI)

  44. Chang CC, South S, Warren D, Jones J, Moser AB, Moser HW, Gould SJ (1999) Metabolic control of peroxisome abundance. Journal of Cell Science 112:1579-1590. (May, 1999) (SCI)

  45. Chang CC and Gould SJ (1998) Phenotype-genotype relationships in complementation group 3 of the peroxisome biogenesis disorders. The American Journal of Human Genetics 63:1294-1306. (Nov., 1998) (SCI)

  46. Chang CC, Lee WH, Moser H, Valle D, Gould SJ (1997) Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogensis disorders. Nature Genetics 15:385-388. (April, 1997) (SCI)

  47. Yen JJ, Hsieh YC, Yen CL, Chang CC, Lin S, Yang-Yen HF (1995) Restoring the apoptosis suppression response to IL-5 confers on erythroleukemic cells a phenotype of IL-5-dependent growth. Journal of Immunology 154:2144-2152. (Mar., 1995) (SCI)

  48. Chang CC, Lin CN, Lin JY (1992) Inhibition of Moloney murine leukemia virus reverse transcriptase activity by tetrahydroxyxanthones isolated from the Chinese herb, Tripterospermum lanceolatum (Hyata). Antiviral Research 19:119-127. (Aug., 1992) (SCI)

 

B.專書及專書論文

  1. Chang CC, and Gould, S. J. (2001) PEX genes, in The Encyclopedia of Molecular Medicine, ed. Creighton, T. E. John Wiley & Sons. (專書)

  2. Chang CC (2000) Analysis of PEX12, a central component of the peroxisomal protein import apparatus and a gene defective in the peroxisome biogenesis disorders. Ph.D. dissertation (博士論文)

 

C.研討會論文

  1. Huang CW, Tsai CY, Chang CC* (2015) Biological significance and mechanistic study on obatoclax-induced downregulation of survivin in human colon cancer cell lines. 30th Joint Annual Conference of Biomedical Sciences, Taipei, TAIWAN, March 21-22. (*: corresponding author)

(Oral presentation; 佳作獎)

  1. Tsai YR, Cai JY, Chang CC* (2014) α-Mangostin destabilizes anti-apoptotic MCL-1 through ERK inhibition to induce apoptosis in human melanoma cell lines and inhibits in vivo B16-F10 melanoma growth. 2014 Taiwan Genomics and Genetics Society (TGGS) annual meeting, Nantou, TAIWAN, December 20-21. (*: corresponding author)

  2. Chung YK, Ouyang WT, Lin CY, Chang CC* (2014) Sulphorapahne engages the SKP2-p27KIP1 axis to induce antiproliferation in human colon cancer cell lines. 29th Joint Annual Conference of Biomedical Sciences, Taipei, TAIWAN, March 15-24. (*: corresponding author)

  3. Lai JK, Wu HC, Chang CC* (2013) 12-O-tetradecanoylphorbol-13-acetate (TPA) induces cell scattering by upregulating krüppel-like factor 4 (KLF4) through the PKCα-ERK signaling axis. 2013 American Association for Cancer Research (AACR) annual meeting, Washington, D.C., U.S.A., April 6-10. (*: corresponding author)

  4. Chang CY, Lee TH*, Chang CC* (2013) Taurine protects kidney cells from oxidative stress and ameliorates peroxidation-induced inflammatory status. 28th Joint Annual Conference of Biomedical Sciences, Taipei, TAIWAN, March 23-24. (*: corresponding author)

  5. Chang CC*, Hsu CY, Su MY (2012) Resveratrol triggers ROS production to elicit ER stress-induced apoptosis in human lung adenocarcinoma cells. Oral presentation in Organisation for Oncology and Translational Research (OOTR) the 8th Annual Conference, Kyoto, JAPAN, April 20-21. (*: corresponding author)

  6. Pan MY, Chang CC* (2012) Essential role of ER stress-induced apoptosis in the anti-cancer effect of prodigiosin on human breast cancer cells. Oral presentation in the 27th Joint Annual Conference of Biomedical Sciences, Taipei, TAIWAN, March 17-18. (*: corresponding author)

  7. Yang SY, Wu TW, Chang CC* (2012) Proapoptotic effect and the underlying mechanisms of Subamolide B on human squamous cell carcinoma cells. Oral presentation in the 27th Joint Annual Conference of Biomedical Sciences, Taipei, TAIWAN, March 17-18. (*: corresponding author)

  8. Chang CC*, Lin SC, Peng YT (2011) Involvement of DNA repair protein RAD51 in the cytotoxicity induced by the anticancer agent prodigiosin. Organisation for Oncology and Translational Research (OOTR) the 7th Annual Conference, Hong Kong, May 13-14.     (*: corresponding author)

  9. Peng YT, Pan MY, Lu CH, Ho TF, Chang CC* (2011) The anticancer agent prodigiosin up-regulates activating transcription factor 3 (ATF3) to induce apoptosis. 26th Joint Annual Conference of Biomedical Sciences, Taipei, TAIWAN, March 19-20. (*: corresponding author)

  10. Feng BL, Lin SC, Lu CH, Peng YT, Wu CH, Shen YC, Tang PC, Ho TF, Chang JS, Chang CC* (2010) Essential role of JNK and p38 MAPK in apoptosis induction by the anticancer agent undecylprodigiosin through TRAIL- and mitochondria-dependent apoptotic pathways. 25th Joint Annual Conference of Biomedical Sciences, Taipei, TAIWAN, March 27-28. (*: corresponding author)

  11. Ho TF, Peng YT, Chuang SM, Lin SC, Feng BL, Lu CH, Yu WJ, Chang JS, Chang CC* (2009) Prodigiosin sensitizes cells to paclitaxel by down-regulating survivin in breast cancer cells. 2009 American Association for Cancer Research (AACR) annual meeting (AACR 100th Annual Meeting 2009), Denver, Colorado, U.S.A., April 18-22. (*: corresponding author)

  12. Ho TF, Peng YT, Chuang SM, Lin SC, Feng BL, Lu CH, Yu WJ, Chang JS, Chang CC* (2009) Prodigiosin enhances paclitaxel drug efficacy against human breast carcinoma cell lines. 24th Joint Annual Conference of Biomedical Sciences, Taipei, TAIWAN, March 21-22. (*: corresponding author)

  13. Chang CC*, Ma CJ, Yang PC, Chen JJW (2008) Invasion-promoting effect of Krüppel-like factor 4 on non-small cell lung cancer cells. 2008 American Association for Cancer Research (AACR) annual meeting, San Diego, California, U.S.A., April 12-16. (*: corresponding author)

  14. Ho TF, Tsai YT, Wei YH, Chang JS, Ma CJ, Yen HE, Chang CC* (2008) The role of IAPs in prodigiosin-induced apoptosis in breast carcinoma cells. 23rd Joint Annual Conference of Biomedical Sciences, Taipei, TAIWAN, March 29-30. (*: corresponding author)

  15. Ho TF. Tsai YT, Wei YH, Chang JS, Ma CJ, Yen HE, Chang CC* (2007) Selective proapoptotic effect of undecylprodigiosin on human breast cancer cell lines. 22nd Joint Annual Conference of Biomedical Sciences, Taipei, TAIWAN, March 17-18. (*: corresponding author)

  16. Chen CH, Chang CC, Shen YC (2007) Studies on the anti-inflammatory effects and mechanisms of andrographolide in microglial cells and stroked rats. 22nd Joint Annual Conference of Biomedical Sciences, Taipei, TAIWAN, March 17-18.

  17. Chang CC, Warren D, Sackstede, K, Gould SJ (1999) PEX12 interacts with PEX5 and PEX10 in peroxisomal matrix protein import. 39th American society for cell biology annual meeting, Washington, D.C., U.S.A., December 11-15; Molecular Biology of the Cell, Vol. 10, Supplement.

  18. Chang CC and Gould SJ (1998) Phenotype-genotype relationships in complementation group 3 of the peroxisome biogenesis disorders. 48th Annual meeting of The American society of Human genetics, Denver, Colorado, U.S.A., October 27-31; The American Journal of Human Genetics Vol. 63, Supplement.

  19. Chang CC and Gould SJ (1997) Mutation analysis of human PEX12 in group 3 patients of the peroxisome biogenesis disorders. 37th American society for cell biology annual meeting, Washington, D.C., U.S.A., December 13-17; Molecular Biology of the Cell, Vol. 8, Supplement.

 

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